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MolNFT v1 · #540456 · protein

AlphaFold monomer V2.0 prediction for zinc finger fyve domain- containing protein 16 (Q7Z3T8)

Q7Z3T8 · Zinc finger fyve domain-containing protein 16: “AlphaFold monomer V2.0 prediction for zinc finger fyve domain- containing protein 16 (Q7Z3T8)”. 14 pockets (best druggability 0.77). MolNFT v1 #540456 on GenesisL1: 3D structure…

Accession
Q7Z3T8
Type
protein
Length
1,539 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
Molecule
Zinc finger fyve domain-containing protein 16
UniProt
Q7Z3T8
Pockets
14 · best druggability 0.77

Structure

1 distinct chain · 13% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AZinc finger fyve domain-containing protein 16protein153913% helix, 13% strandQ7Z3T8

Pockets

14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19400.770.79104empty
25060.640.7638empty
33070.560.7632empty
4800.520.8520empty
51970.450.7326empty

Compared structures

  • 3T7L · Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 3T7L · Crystal structure of the fyve domain of endofin (ZFYVE16) at 1.1A resolution · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 5MK0 · Crystal structure of the his domain protein tyrosine phosphatase (hd- PTP/PTPN23) BRO1… · an experimental structure of the same protein · chain A against B, TM-score 0.01

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