MolNFT v1 · #540396 · protein

AlphaFold monomer V2.0 prediction for zinc finger protein 57 (Q8C6P8)

Q8C6P8: “AlphaFold monomer V2.0 prediction for zinc finger protein 57 (Q8C6P8)”. 3 pockets (best druggability 0.55). MolNFT v1 #540396 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8C6P8
Type: protein
Length: 421 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xe53B460B01322174fc73C45BCd0b0a003515f3e4
Molecule: Zinc finger protein 57
UniProt: Q8C6P8
Pockets: 3 · best druggability 0.55

Structure

1 distinct chain · 25% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc finger protein 57	protein	421	25% helix, 5% strand	Q8C6P8

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	306	0.55	0.75	29	empty
2	161	0.42	0.74	21	empty
3	70	0.29	0.73	13	empty

Compared structures

4M9V · Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA · an experimental structure of the same protein · chain A against C, TM-score 0.14
4M9V · ZFP57 mutant (E182Q) in complex with 5-carboxylcytosine DNA · an experimental structure of the same protein · chain A against C, TM-score 0.14
4GZN · Mouse ZFP57 zinc fingers in complex with methylated DNA · an experimental structure of the same protein · chain A against C, TM-score 0.13
4GZN · Mouse ZFP57 zinc fingers in complex with methylated DNA · an experimental structure of the same protein · chain A against C, TM-score 0.13

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8C6P8
Elsewhere: UniProt Q8C6P8 · AlphaFold DB Q8C6P8

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