MolNFT v1 · #538137 · protein

AlphaFold monomer V2.0 prediction for uncharacterized protein ZK177.8 (Q09374)

Q09374: “AlphaFold monomer V2.0 prediction for uncharacterized protein ZK177.8 (Q09374)”. 5 pockets (best druggability 0.73). MolNFT v1 #538137 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q09374
Type: protein
Length: 587 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x461648775Eca78dA7a98b9488A0e39e25b483D17
Molecule: Uncharacterized protein ZK177.8
UniProt: Q09374
Pockets: 5 · best druggability 0.73

Structure

1 distinct chain · 50% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein ZK177.8	protein	587	50% helix, 10% strand	Q09374

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	886	0.73	0.78	65	empty
2	155	0.47	0.76	28	empty
3	76	0.46	0.82	16	empty
4	66	0.30	0.74	15	empty
5	54	0.26	0.73	16	empty

Compared structures

6PWY · Structure of C. elegans ZK177.8, SAMHD1 ortholog · an experimental structure of the same protein · chain A against B, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q09374
Elsewhere: UniProt Q09374 · AlphaFold DB Q09374

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