MolNFT v1 · #534829 · protein
AlphaFold monomer V2.0 prediction for phosphoinositide 3-phosphatase (O13819)
O13819: “AlphaFold monomer V2.0 prediction for phosphoinositide 3-phosphatase (O13819)”. 10 pockets (best druggability 0.66). MolNFT v1 #534829 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O13819
- Type
- protein
- Length
- 559 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
- Molecule
- Phosphoinositide 3-phosphatase
- UniProt
- O13819
- Pockets
- 10 · best druggability 0.66
Structure
1 distinct chain · 42% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoinositide 3-phosphatase | protein | 559 | 42% helix, 16% strand | O13819 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.66 | 0.96 | 19 | empty |
| 2 | 256 | 0.63 | 0.82 | 33 | empty |
| 3 | 196 | 0.57 | 0.80 | 22 | empty |
| 4 | 189 | 0.49 | 0.76 | 29 | empty |
| 5 | 154 | 0.47 | 0.77 | 25 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O13819
- Elsewhere: UniProt O13819 · AlphaFold DB O13819
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