MolNFT v1 · #502253 · protein

AlphaFold monomer V2.0 prediction for xylose isomerase (P19148)

P19148: “AlphaFold monomer V2.0 prediction for xylose isomerase (P19148)”. 4 pockets (best druggability 0.59). MolNFT v1 #502253 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P19148
Type: protein
Length: 439 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
Molecule: Xylose isomerase
UniProt: P19148
Pockets: 4 · best druggability 0.59

Structure

1 distinct chain · 49% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Xylose isomerase	protein	439	49% helix, 13% strand	P19148

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	362	0.59	0.76	36	empty
2	133	0.41	0.75	20	empty
3	73	0.36	0.77	17	empty
4	56	0.30	0.76	16	empty

Compared structures

1A0C · Xylose isomerase from thermoanaerobacterium thermosulfurigenes · an experimental structure of the same protein · chain A against A, TM-score 0.99
1A0C · Xylose isomerase from thermoanaerobacterium thermosulfurigenes · an experimental structure of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19148
Elsewhere: UniProt P19148 · AlphaFold DB P19148

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.