MolNFT v1 · #502158 · protein

AlphaFold monomer V2.0 prediction for xylose isomerase (P54273)

P54273: “AlphaFold monomer V2.0 prediction for xylose isomerase (P54273)”. 5 pockets (best druggability 0.73). MolNFT v1 #502158 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P54273
Type: protein
Length: 441 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xb08BD8EEBA81B2359dcA82AB1Dd8761EEe36263F
Molecule: Xylose isomerase
UniProt: P54273
Pockets: 5 · best druggability 0.73

Structure

1 distinct chain · 49% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Xylose isomerase	protein	441	49% helix, 12% strand	P54273

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	72	0.73	0.97	25	empty
2	401	0.61	0.77	44	empty
3	170	0.46	0.75	18	empty
4	72	0.37	0.77	19	empty
5	80	0.37	0.77	17	empty

Compared structures

1A0D · Xylose isomerase from bacillus stearothermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.99
1A0D · Xylose isomerase from bacillus stearothermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P54273
Elsewhere: UniProt P54273 · AlphaFold DB P54273

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