MolNFT v1 · #500562 · protein
AlphaFold monomer V2.0 prediction for tyrosine-protein kinase wzc (P76387)
P76387: “AlphaFold monomer V2.0 prediction for tyrosine-protein kinase wzc (P76387)”. 7 pockets (best druggability 0.64). MolNFT v1 #500562 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P76387
- Type
- protein
- Length
- 720 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- Tyrosine-protein kinase wzc
- UniProt
- P76387
- Pockets
- 7 · best druggability 0.64
Structure
1 distinct chain · 50% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase wzc | protein | 720 | 50% helix, 18% strand | P76387 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 584 | 0.64 | 0.75 | 59 | empty |
| 2 | 491 | 0.61 | 0.75 | 47 | empty |
| 3 | 355 | 0.59 | 0.76 | 48 | empty |
| 4 | 137 | 0.50 | 0.79 | 21 | empty |
| 5 | 129 | 0.40 | 0.74 | 18 | empty |
Compared structures
- 3LA6 · Octameric kinase domain of the E. COLI tyrosine kinase wzc with bound ADP · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 3LA6 · Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP · an experimental structure of the same protein · chain A against B, TM-score 0.36
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P76387
- Elsewhere: UniProt P76387 · AlphaFold DB P76387
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