MolNFT v1 · #499950 · protein
AlphaFold monomer V2.0 prediction for probable SERINE/THREONINE- protein kinase WNK1 (A2YMV6)
A2YMV6 · Probable SERINE/THREONINE-protein kinase WNK1: “AlphaFold monomer V2.0 prediction for probable SERINE/THREONINE- protein kinase WNK1 (A2YMV6)”. 9 pockets (best druggability 0.80). MolNFT v1 #499950 on GenesisL1: 3D structure…
- Accession
- A2YMV6
- Type
- protein
- Length
- 704 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x995f1a3568169CB9DbdB48430AEeec5E5696A9E4
- Molecule
- Probable SERINE/THREONINE-protein kinase WNK1
- UniProt
- A2YMV6
- Pockets
- 9 · best druggability 0.80
Structure
1 distinct chain · 24% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable SERINE/THREONINE-protein kinase WNK1 | protein | 704 | 24% helix, 12% strand | A2YMV6 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 490 | 0.80 | 0.87 | 50 | empty |
| 2 | 87 | 0.66 | 0.91 | 20 | empty |
| 3 | 193 | 0.64 | 0.84 | 30 | empty |
| 4 | 234 | 0.53 | 0.77 | 31 | empty |
| 5 | 79 | 0.50 | 0.83 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2YMV6
- Elsewhere: UniProt A2YMV6 · AlphaFold DB A2YMV6
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