MolNFT v1 · #499949 · protein

AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK1 (P83741)

P83741: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK1 (P83741)”. 5 pockets (best druggability 0.75). MolNFT v1 #499949 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P83741
Type: protein
Length: 2,377 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x41f14059A2ce2B9bfD2DFE723f11dad3eCa2614e
Molecule: SERINE/THREONINE-protein kinase WNK1
UniProt: P83741
Pockets: 5 · best druggability 0.75

Structure

1 distinct chain · 11% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase WNK1	protein	2377	11% helix, 4% strand	P83741

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	776	0.75	0.80	64	empty
2	111	0.42	0.77	19	empty
3	81	0.33	0.75	20	empty
4	70	0.32	0.75	12	empty
5	58	0.26	0.73	14	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P83741
Elsewhere: UniProt P83741 · AlphaFold DB P83741

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