MolNFT v1 · #499864 · protein
AlphaFold monomer V2.0 prediction for MAP kinase kinase kinase WIN1 (O74304)
O74304: “AlphaFold monomer V2.0 prediction for MAP kinase kinase kinase WIN1 (O74304)”. 11 pockets (best druggability 0.78). MolNFT v1 #499864 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O74304
- Type
- protein
- Length
- 1,436 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97AD768995300e55b4CD8aaef33b93A4B7B3153A
- Molecule
- MAP kinase kinase kinase WIN1
- UniProt
- O74304
- Pockets
- 11 · best druggability 0.78
Structure
1 distinct chain · 47% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MAP kinase kinase kinase WIN1 | protein | 1436 | 47% helix, 6% strand | O74304 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 862 | 0.78 | 0.81 | 61 | empty |
| 2 | 839 | 0.73 | 0.77 | 66 | empty |
| 3 | 252 | 0.63 | 0.81 | 36 | empty |
| 4 | 573 | 0.62 | 0.74 | 48 | empty |
| 5 | 176 | 0.50 | 0.77 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74304
- Elsewhere: UniProt O74304 · AlphaFold DB O74304
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