GL1X · GenesisL1 explorer

MolNFT v1 · #499195 · protein

AlphaFold monomer V2.0 prediction for gator complex protein WDR59 (Q6PJI9)

Q6PJI9: “AlphaFold monomer V2.0 prediction for gator complex protein WDR59 (Q6PJI9)”. 12 pockets (best druggability 0.75). MolNFT v1 #499195 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q6PJI9
Type
protein
Length
974 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x3df429dC3a3eF55192Fa727Bf390982f8ea756Df
Molecule
Gator complex protein WDR59
UniProt
Q6PJI9
Pockets
12 · best druggability 0.75

Structure

1 distinct chain · 23% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGator complex protein WDR59protein97423% helix, 23% strandQ6PJI9

Pockets

12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16730.750.8166empty
26440.710.7871empty
32040.570.8027empty
42030.510.7627empty
52400.500.7531empty

Compared structures

  • 7UHY · Human GATOR2 complex · an experimental structure of the same protein · chain A against D, TM-score 0.24
  • 7UHY · Human GATOR2 complex · an experimental structure of the same protein · chain A against D, TM-score 0.24

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