MolNFT v1 · #499161 · protein

AlphaFold monomer V2.0 prediction for tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Q7ZY78)

Q7ZY78: “AlphaFold monomer V2.0 prediction for tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4…”. 2 pockets (best druggability 0.81). MolNFT v1 #499161 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q7ZY78
Type: protein
Length: 396 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x3905E99564C71Dc98C1373f42EFf754c4C8cD82d
Molecule: TRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4
UniProt: Q7ZY78
Pockets: 2 · best druggability 0.81

Structure

1 distinct chain · 16% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	protein	396	16% helix, 41% strand	Q7ZY78

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1072	0.81	0.82	77	empty
2	108	0.38	0.75	19	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7ZY78
Elsewhere: UniProt Q7ZY78 · AlphaFold DB Q7ZY78

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