MolNFT v1 · #499127 · protein
AlphaFold monomer V2.0 prediction for wd repeat-containing protein 47 (Q8CGF6)
Q8CGF6: “AlphaFold monomer V2.0 prediction for wd repeat-containing protein 47 (Q8CGF6)”. 11 pockets (best druggability 0.78). MolNFT v1 #499127 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8CGF6
- Type
- protein
- Length
- 920 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xfEbB23e5889f981c58b0c3A97247348dB3e08418
- Molecule
- Wd repeat-containing protein 47
- UniProt
- Q8CGF6
- Pockets
- 11 · best druggability 0.78
Structure
1 distinct chain · 28% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Wd repeat-containing protein 47 | protein | 920 | 28% helix, 20% strand | Q8CGF6 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 359 | 0.78 | 0.88 | 50 | empty |
| 2 | 689 | 0.69 | 0.77 | 59 | empty |
| 3 | 869 | 0.68 | 0.74 | 59 | empty |
| 4 | 160 | 0.55 | 0.80 | 25 | empty |
| 5 | 87 | 0.54 | 0.85 | 17 | empty |
Compared structures
- 7WEJ · Crystal structure of the mouse Wdr47 NTD. · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 7WEK · Crystal structure of the mouse Wdr47 NTD in complex with the WBR motif form Camsap3. · an experimental structure of the same protein · chain A against B, TM-score 0.23
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8CGF6
- Elsewhere: UniProt Q8CGF6 · AlphaFold DB Q8CGF6
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