MolNFT v1 · #499114 · protein
AlphaFold monomer V2.0 prediction for wd repeat-containing protein 41 (Q9HAD4)
Q9HAD4: “AlphaFold monomer V2.0 prediction for wd repeat-containing protein 41 (Q9HAD4)”. 3 pockets (best druggability 0.66). MolNFT v1 #499114 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9HAD4
- Type
- protein
- Length
- 459 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Wd repeat-containing protein 41
- UniProt
- Q9HAD4
- Pockets
- 3 · best druggability 0.66
Structure
1 distinct chain · 5% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Wd repeat-containing protein 41 | protein | 459 | 5% helix, 44% strand | Q9HAD4 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 734 | 0.66 | 0.74 | 40 | empty |
| 2 | 66 | 0.37 | 0.78 | 14 | empty |
| 3 | 55 | 0.34 | 0.78 | 16 | empty |
Compared structures
- 7MGE · Structure of C9ORF72:SMCR8:WDR41 in complex with ARF1 · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 7MGE · Structure of C9orf72:SMCR8:WDR41 in complex with ARF1 · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 6LT0 · Cryo-EM structure of C9ORF72-SMCR8-WDR41 · an experimental structure of the same protein · chain A against A, TM-score 0.71
- 6LT0 · cryo-EM structure of C9ORF72-SMCR8-WDR41 · an experimental structure of the same protein · chain A against A, TM-score 0.71
- 6WHH · Crystal structure of human WDR41 · an experimental structure of the same protein · chain A against A, TM-score 0.71
- 8W3V · Crystal structure of human WDR41 · an experimental structure of the same protein · chain A against B, TM-score 0.70
- 6V4U · Cryo-EM structure of SMCR8-C9orf72-WDR41 complex · an experimental structure of the same protein · chain A against C, TM-score 0.63
- 6V4U · Cryo-EM structure of SMCR8-C9ORF72-WDR41 complex · an experimental structure of the same protein · chain A against C, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HAD4
- Elsewhere: UniProt Q9HAD4 · AlphaFold DB Q9HAD4
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