MolNFT v1 · #498836 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase warts homolog (O45797)
O45797: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase warts homolog (O45797)”. 11 pockets (best druggability 0.78). MolNFT v1 #498836 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O45797
- Type
- protein
- Length
- 908 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBF0D2e107Ce1EcD2C4369B042274201DB719AaAF
- Molecule
- SERINE/THREONINE-protein kinase warts homolog
- UniProt
- O45797
- Pockets
- 11 · best druggability 0.78
Structure
1 distinct chain · 28% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase warts homolog | protein | 908 | 28% helix, 6% strand | O45797 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 759 | 0.78 | 0.82 | 79 | empty |
| 2 | 762 | 0.75 | 0.80 | 83 | empty |
| 3 | 437 | 0.64 | 0.78 | 41 | empty |
| 4 | 125 | 0.54 | 0.81 | 20 | empty |
| 5 | 199 | 0.45 | 0.74 | 29 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O45797
- Elsewhere: UniProt O45797 · AlphaFold DB O45797
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