MolNFT v1 · #497824 · protein
AlphaFold monomer V2.0 prediction for V-type proton ATPase subunit a, golgi isoform (P37296)
P37296: “AlphaFold monomer V2.0 prediction for V-type proton ATPase subunit a, golgi isoform (P37296)”. 12 pockets (best druggability 0.71). MolNFT v1 #497824 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P37296
- Type
- protein
- Length
- 890 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
- Molecule
- V-type proton ATPase subunit a, golgi isoform
- UniProt
- P37296
- Pockets
- 12 · best druggability 0.71
Structure
1 distinct chain · 58% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V-type proton ATPase subunit a, golgi isoform | protein | 890 | 58% helix, 8% strand | P37296 |
Pockets
12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 240 | 0.71 | 0.87 | 32 | empty |
| 2 | 261 | 0.59 | 0.78 | 29 | empty |
| 3 | 165 | 0.56 | 0.81 | 26 | empty |
| 4 | 213 | 0.51 | 0.76 | 26 | empty |
| 5 | 239 | 0.46 | 0.73 | 28 | empty |
Compared structures
- 6O7U · Saccharomyces cerevisiae V-ATPase STV1-vo · an experimental structure of the same protein · chain A against a, TM-score 0.70
- 6O7X · Saccharomyces cerevisiae V-ATPase STV1-V1VO state 3 · an experimental structure of the same protein · chain A against a, TM-score 0.66
- 6O7V · Saccharomyces cerevisiae V-ATPase STV1-V1VO state 1 · an experimental structure of the same protein · chain A against a, TM-score 0.66
- 6O7W · Saccharomyces cerevisiae V-ATPase Stv1-V1VO State 2 · an experimental structure of the same protein · chain A against a, TM-score 0.65
- 6O7W · Saccharomyces cerevisiae V-ATPase STV1-V1VO state 2 · an experimental structure of the same protein · chain A against a, TM-score 0.65
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37296
- Elsewhere: UniProt P37296 · AlphaFold DB P37296
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