MolNFT v1 · #497358 · protein

AlphaFold monomer V2.0 prediction for synaptic vesicular amine transporter (Q8BRU6)

Q8BRU6: “AlphaFold monomer V2.0 prediction for synaptic vesicular amine transporter (Q8BRU6)”. 4 pockets (best druggability 0.76). MolNFT v1 #497358 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8BRU6
Type: protein
Length: 517 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9DC039DF1aC938C188D9b20e6591d287429437BF
Molecule: Synaptic vesicular amine transporter
UniProt: Q8BRU6
Pockets: 4 · best druggability 0.76

Structure

1 distinct chain · 71% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Synaptic vesicular amine transporter	protein	517	71% helix, 2% strand	Q8BRU6

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	72	0.76	0.99	25	empty
2	197	0.52	0.77	33	empty
3	254	0.50	0.74	24	empty
4	107	0.44	0.78	21	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8BRU6
Elsewhere: UniProt Q8BRU6 · AlphaFold DB Q8BRU6

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