MolNFT v1 · #497248 · protein
AlphaFold monomer V2.0 prediction for zinc metalloproteinase- disintegrin-like atrase-B (D6PXE8)
D6PXE8 · Zinc metalloproteinase-disintegrin-like atrase-B: “AlphaFold monomer V2.0 prediction for zinc metalloproteinase- disintegrin-like atrase-B (D6PXE8)”. 6 pockets (best druggability 0.73). MolNFT v1 #497248 on GenesisL1: 3D…
- Accession
- D6PXE8
- Type
- protein
- Length
- 593 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- Zinc metalloproteinase-disintegrin-like atrase-B
- UniProt
- D6PXE8
- Pockets
- 6 · best druggability 0.73
Structure
1 distinct chain · 19% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc metalloproteinase-disintegrin-like atrase-B | protein | 593 | 19% helix, 26% strand | D6PXE8 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 651 | 0.73 | 0.80 | 78 | empty |
| 2 | 282 | 0.66 | 0.82 | 50 | empty |
| 3 | 124 | 0.39 | 0.75 | 21 | empty |
| 4 | 71 | 0.38 | 0.78 | 17 | empty |
| 5 | 57 | 0.35 | 0.78 | 13 | empty |
Modifications
Observed in the structure: 16 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D6PXE8
- Elsewhere: UniProt D6PXE8 · AlphaFold DB D6PXE8
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