MolNFT v1 · #497229 · protein
AlphaFold monomer V2.0 prediction for zinc metalloproteinase- disintegrin-like MTP8 (F8RKW0)
F8RKW0 · Zinc metalloproteinase-disintegrin-like MTP8: “AlphaFold monomer V2.0 prediction for zinc metalloproteinase- disintegrin-like MTP8 (F8RKW0)”. 10 pockets (best druggability 0.70). MolNFT v1 #497229 on GenesisL1: 3D structure…
- Accession
- F8RKW0
- Type
- protein
- Length
- 613 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8841A75A4374915eB1e3A60827149042327e3c89
- Molecule
- Zinc metalloproteinase-disintegrin-like MTP8
- UniProt
- F8RKW0
- Pockets
- 10 · best druggability 0.70
Structure
1 distinct chain · 19% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc metalloproteinase-disintegrin-like MTP8 | protein | 613 | 19% helix, 27% strand | F8RKW0 |
Pockets
10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 334 | 0.70 | 0.84 | 44 | empty |
| 2 | 467 | 0.67 | 0.79 | 61 | empty |
| 3 | 138 | 0.64 | 0.87 | 27 | empty |
| 4 | 248 | 0.62 | 0.81 | 31 | empty |
| 5 | 228 | 0.60 | 0.80 | 36 | empty |
Modifications
Observed in the structure: 19 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F8RKW0
- Elsewhere: UniProt F8RKW0 · AlphaFold DB F8RKW0
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