MolNFT v1 · #496406 · protein
AlphaFold monomer V2.0 prediction for villin-4 (O65570)
O65570: “AlphaFold monomer V2.0 prediction for villin-4 (O65570)”. 17 pockets (best druggability 0.78). MolNFT v1 #496406 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O65570
- Type
- protein
- Length
- 974 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x52c78725AFC9d48D15F59Ad16EF89e5653209d57
- Molecule
- Villin-4
- UniProt
- O65570
- Pockets
- 17 · best druggability 0.78
Structure
1 distinct chain · 24% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Villin-4 | protein | 974 | 24% helix, 21% strand | O65570 |
Pockets
17 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 831 | 0.78 | 0.82 | 91 | empty |
| 2 | 103 | 0.76 | 0.97 | 20 | empty |
| 3 | 650 | 0.68 | 0.77 | 59 | empty |
| 4 | 214 | 0.61 | 0.82 | 28 | empty |
| 5 | 132 | 0.50 | 0.79 | 21 | empty |
Compared structures
- 5VNT · Solution NMR structure of the C-terminal headpiece domain of villin 4 from A.THALIANA… · an experimental structure of the same protein · chain A against A, TM-score 0.06
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O65570
- Elsewhere: UniProt O65570 · AlphaFold DB O65570
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