MolNFT v1 · #496389 · protein
AlphaFold monomer V2.0 prediction for vacuolar import and degradation protein 28 (P40547)
P40547: “AlphaFold monomer V2.0 prediction for vacuolar import and degradation protein 28 (P40547)”. 11 pockets (best druggability 0.67). MolNFT v1 #496389 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40547
- Type
- protein
- Length
- 921 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x882B14FbCEd9AA8538F421f0Fc2Be75789f3B8A0
- Molecule
- Vacuolar import and degradation protein 28
- UniProt
- P40547
- Pockets
- 11 · best druggability 0.67
Structure
1 distinct chain · 59% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vacuolar import and degradation protein 28 | protein | 921 | 59% helix, 2% strand | P40547 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 562 | 0.67 | 0.77 | 54 | empty |
| 2 | 311 | 0.64 | 0.80 | 30 | empty |
| 3 | 425 | 0.59 | 0.75 | 48 | empty |
| 4 | 231 | 0.52 | 0.76 | 31 | empty |
| 5 | 101 | 0.50 | 0.82 | 22 | empty |
Compared structures
- 6SWY · Structure of active gid E3 ubiquitin ligase complex minus GID2 and delta GID9 ring domain · an experimental structure of the same protein · chain A against 5, TM-score 0.85
- 7WUG · Gid subcomplex: GID12 bound substrate receptor scaffolding module · an experimental structure of the same protein · chain A against 5, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40547
- Elsewhere: UniProt P40547 · AlphaFold DB P40547
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