MolNFT v1 · #496224 · protein
AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor kdr-like (Q8AXB3)
Q8AXB3: “AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor kdr-like (Q8AXB3)”. 9 pockets (best druggability 0.74). MolNFT v1 #496224 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8AXB3
- Type
- protein
- Length
- 1,302 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x60C72ad9D455B17009020cE827574DBF55868757
- Molecule
- Vascular endothelial growth factor receptor kdr-like
- UniProt
- Q8AXB3
- Pockets
- 9 · best druggability 0.74
Structure
1 distinct chain · 16% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vascular endothelial growth factor receptor kdr-like | protein | 1302 | 16% helix, 35% strand | Q8AXB3 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 745 | 0.74 | 0.79 | 88 | empty |
| 2 | 948 | 0.74 | 0.77 | 86 | empty |
| 3 | 829 | 0.73 | 0.78 | 81 | empty |
| 4 | 216 | 0.47 | 0.74 | 22 | empty |
| 5 | 89 | 0.43 | 0.80 | 17 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8AXB3
- Elsewhere: UniProt Q8AXB3 · AlphaFold DB Q8AXB3
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