MolNFT v1 · #496222 · protein
AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor 3 (P35917)
P35917: “AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor 3 (P35917)”. 16 pockets (best druggability 0.76). MolNFT v1 #496222 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P35917
- Type
- protein
- Length
- 1,363 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
- Molecule
- Vascular endothelial growth factor receptor 3
- UniProt
- P35917
- Pockets
- 16 · best druggability 0.76
Structure
1 distinct chain · 17% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vascular endothelial growth factor receptor 3 | protein | 1363 | 17% helix, 32% strand | P35917 |
Pockets
16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 992 | 0.76 | 0.78 | 87 | empty |
| 2 | 695 | 0.69 | 0.77 | 59 | empty |
| 3 | 273 | 0.55 | 0.77 | 33 | empty |
| 4 | 98 | 0.50 | 0.82 | 15 | empty |
| 5 | 89 | 0.44 | 0.80 | 16 | empty |
Modifications
Observed in the structure: 10 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35917
- Elsewhere: UniProt P35917 · AlphaFold DB P35917
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