MolNFT v1 · #496218 · protein
AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor 2 (O08775)
O08775: “AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor 2 (O08775)”. 11 pockets (best druggability 0.72). MolNFT v1 #496218 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O08775
- Type
- protein
- Length
- 1,343 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB35df660264f41795De49C83276C108A4ba91ADE
- Molecule
- Vascular endothelial growth factor receptor 2
- UniProt
- O08775
- Pockets
- 11 · best druggability 0.72
Structure
1 distinct chain · 15% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vascular endothelial growth factor receptor 2 | protein | 1343 | 15% helix, 33% strand | O08775 |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 674 | 0.72 | 0.79 | 57 | empty |
| 2 | 721 | 0.71 | 0.77 | 69 | empty |
| 3 | 345 | 0.63 | 0.79 | 41 | empty |
| 4 | 384 | 0.56 | 0.74 | 45 | empty |
| 5 | 54 | 0.51 | 0.87 | 14 | empty |
Modifications
Observed in the structure: 10 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O08775
- Elsewhere: UniProt O08775 · AlphaFold DB O08775
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