MolNFT v1 · #496056 · protein

AlphaFold monomer V2.0 prediction for vascular endothelial growth factor D (O43915)

O43915: “AlphaFold monomer V2.0 prediction for vascular endothelial growth factor D (O43915)”. 3 pockets (best druggability 0.49). MolNFT v1 #496056 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O43915
Type: protein
Length: 354 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x779b368283e79942739fEb126753AC2b434CE90e
Molecule: Vascular endothelial growth factor D
UniProt: O43915
Pockets: 3 · best druggability 0.49

Structure

1 distinct chain · 28% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vascular endothelial growth factor D	protein	354	28% helix, 25% strand	O43915

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	220	0.49	0.75	24	empty
2	140	0.49	0.79	22	empty
3	76	0.38	0.77	15	empty

Modifications

Observed in the structure: 13 disulfide (disulfide).

Compared structures

2XV7 · Crystal structure of vascular endothelial growth factor D · an experimental structure of the same protein · chain A against A, TM-score 0.28
2XV7 · Crystal structure of vascular endothelial growth factor D · an experimental structure of the same protein · chain A against A, TM-score 0.28

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43915
Elsewhere: UniProt O43915 · AlphaFold DB O43915

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