MolNFT v1 · #495991 · protein
AlphaFold monomer V2.0 prediction for vitamin D3 receptor a (Q9PTN2)
Q9PTN2: “AlphaFold monomer V2.0 prediction for vitamin D3 receptor a (Q9PTN2)”. 5 pockets (best druggability 0.85). MolNFT v1 #495991 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9PTN2
- Type
- protein
- Length
- 453 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBF0D2e107Ce1EcD2C4369B042274201DB719AaAF
- Molecule
- Vitamin D3 receptor a
- UniProt
- Q9PTN2
- Pockets
- 5 · best druggability 0.85
Structure
1 distinct chain · 50% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vitamin D3 receptor a | protein | 453 | 50% helix, 3% strand | Q9PTN2 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 281 | 0.85 | 0.96 | 37 | empty |
| 2 | 222 | 0.53 | 0.77 | 24 | empty |
| 3 | 156 | 0.49 | 0.78 | 23 | empty |
| 4 | 146 | 0.48 | 0.78 | 20 | empty |
| 5 | 126 | 0.35 | 0.73 | 19 | empty |
Compared structures
- 3DR1 · Side-chain fluorine atoms of non-steroidal vitamin D3 analogs stabilize helix 12 of… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 3DR1 · Side-chain fluorine atoms of non-steroidal vitamin D3 analogs stabilize helix 12 of… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 6XZI · Structure of zvdr lbd-calcitriol in complex with chimera 11 · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 6FO7 · Vitamin D nuclear receptor complex 3 · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 8PWE · Crystal structure of VDR complex with Novel Des-C-Ring and Aromatic-D-Ring analog 3a · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 6XZH · Structure of zvdr lbd-calcitriol in complex with chimera 10 · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 5OW9 · Vitamin D receptor complex · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 6FO9 · Vitamin D nuclear receptor complex 2 · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 5E7V · Potent vitamin D receptor agonist · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 5E7V · Potent Vitamin D Receptor Agonist · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 4FHH · Development of synthetically accessible non-secosteroidal hybrid molecules combining… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 4FHH · Development of synthetically accessible non-secosteroidal hybrid molecules combining… · an experimental structure of the same protein · chain A against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9PTN2
- Elsewhere: UniProt Q9PTN2 · AlphaFold DB Q9PTN2
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