MolNFT v1 · #495843 · protein
AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor VAV3 (Q9R0C8)
Q9R0C8: “AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor VAV3 (Q9R0C8)”. 6 pockets (best druggability 0.77). MolNFT v1 #495843 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9R0C8
- Type
- protein
- Length
- 847 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xE1b961cFdddF7335AbA492F1fc32079dEd2c4285
- Molecule
- Guanine nucleotide exchange factor VAV3
- UniProt
- Q9R0C8
- Pockets
- 6 · best druggability 0.77
Structure
1 distinct chain · 40% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine nucleotide exchange factor VAV3 | protein | 847 | 40% helix, 19% strand | Q9R0C8 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 768 | 0.77 | 0.81 | 67 | empty |
| 2 | 663 | 0.66 | 0.75 | 52 | empty |
| 3 | 232 | 0.48 | 0.74 | 32 | empty |
| 4 | 83 | 0.41 | 0.78 | 18 | empty |
| 5 | 70 | 0.33 | 0.75 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9R0C8
- Elsewhere: UniProt Q9R0C8 · AlphaFold DB Q9R0C8
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