MolNFT v1 · #494984 · protein
AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase vasa (P09052)
P09052: “AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase vasa (P09052)”. 7 pockets (best druggability 0.80). MolNFT v1 #494984 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P09052
- Type
- protein
- Length
- 661 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x698328354703946bB87B53D91FAf87CCd5315F42
- Molecule
- ATP-dependent RNA helicase vasa
- UniProt
- P09052
- Pockets
- 7 · best druggability 0.80
Structure
1 distinct chain · 27% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATP-dependent RNA helicase vasa | protein | 661 | 27% helix, 10% strand | P09052 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1066 | 0.80 | 0.82 | 81 | empty |
| 2 | 150 | 0.51 | 0.79 | 28 | empty |
| 3 | 208 | 0.49 | 0.76 | 29 | empty |
| 4 | 178 | 0.48 | 0.77 | 30 | empty |
| 5 | 106 | 0.40 | 0.76 | 16 | empty |
Compared structures
- 2DB3 · Structural basis for RNA unwinding by the dead-box protein drosophila vasa · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 2DB3 · Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 5NT7 · Structure of the LOTUS domain of Oskar in complex with the C-terminal RecA-like domain of… · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 5NT7 · Structure of the lotus domain of oskar in complex with the C-terminal reca-like domain of… · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 2IHS · Crystal structure of the B30.2/SPRY domain of GUSTAVUS in complex with a 20-residue VASA… · an experimental structure of the same protein · chain A against D, TM-score 0.02
- 2IHS · Crystal structure of the B30.2/SPRY domain of gustavus in complex with a 20-residue vasa… · an experimental structure of the same protein · chain A against D, TM-score 0.02
- 3F2O · Crystal structure of human SPLA/RYANODINE receptor domain and socs box containing 1… · an experimental structure of the same protein · chain A against C, TM-score 0.02
- 3F2O · Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1… · an experimental structure of the same protein · chain A against C, TM-score 0.02
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09052
- Elsewhere: UniProt P09052 · AlphaFold DB P09052
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