MolNFT v1 · #494691 · protein
AlphaFold monomer V2.0 prediction for ephrin receptor 1 (O61460)
O61460: “AlphaFold monomer V2.0 prediction for ephrin receptor 1 (O61460)”. 14 pockets (best druggability 0.74). MolNFT v1 #494691 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O61460
- Type
- protein
- Length
- 1,122 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4312c32c7eA2564E3D5896f13870F2A4F29Ec1f2
- Molecule
- Ephrin receptor 1
- UniProt
- O61460
- Pockets
- 14 · best druggability 0.74
Structure
1 distinct chain · 21% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ephrin receptor 1 | protein | 1122 | 21% helix, 25% strand | O61460 |
Pockets
14 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 590 | 0.74 | 0.81 | 58 | empty |
| 2 | 307 | 0.58 | 0.77 | 37 | empty |
| 3 | 400 | 0.55 | 0.73 | 46 | empty |
| 4 | 181 | 0.49 | 0.76 | 24 | empty |
| 5 | 173 | 0.48 | 0.76 | 21 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O61460
- Elsewhere: UniProt O61460 · AlphaFold DB O61460
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