MolNFT v1 · #493026 · protein
AlphaFold monomer V2.0 prediction for U3 small nucleolar RNA- associated protein 4 (Q06679)
Q06679 · U3 small nucleolar RNA-associated protein 4: “AlphaFold monomer V2.0 prediction for U3 small nucleolar RNA- associated protein 4 (Q06679)”. 12 pockets (best druggability 0.84). MolNFT v1 #493026 on GenesisL1: 3D structure, binding…
- Accession
- Q06679
- Type
- protein
- Length
- 776 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x650D212bc55D555afec5187BC0cCdFF33c39C025
- Molecule
- U3 small nucleolar RNA-associated protein 4
- UniProt
- Q06679
- Pockets
- 12 · best druggability 0.84
Structure
1 distinct chain · 7% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | U3 small nucleolar RNA-associated protein 4 | protein | 776 | 7% helix, 42% strand | Q06679 |
Pockets
12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 879 | 0.84 | 0.86 | 55 | empty |
| 2 | 848 | 0.83 | 0.85 | 76 | empty |
| 3 | 224 | 0.75 | 0.90 | 36 | empty |
| 4 | 284 | 0.65 | 0.82 | 31 | empty |
| 5 | 479 | 0.63 | 0.76 | 40 | empty |
Compared structures
- 5WLC · The complete structure of the small subunit processome · an experimental structure of the same protein · chain A against LN, TM-score 0.86
- 6ZQB · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state B2 · an experimental structure of the same protein · chain A against UD, TM-score 0.85
- 6ZQC · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 · an experimental structure of the same protein · chain A against UD, TM-score 0.85
- 7AJT · Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) · an experimental structure of the same protein · chain A against UD, TM-score 0.85
- 6ZQA · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state A… · an experimental structure of the same protein · chain A against UD, TM-score 0.85
- 6ZQD · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1 · an experimental structure of the same protein · chain A against UD, TM-score 0.84
- 7AJU · Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) · an experimental structure of the same protein · chain A against UD, TM-score 0.84
- 6ZQE · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A… · an experimental structure of the same protein · chain A against UD, TM-score 0.84
- 6LQT · Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) · an experimental structure of the same protein · chain A against A4, TM-score 0.84
- 6LQS · Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) · an experimental structure of the same protein · chain A against A4, TM-score 0.84
- 6LQQ · Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) · an experimental structure of the same protein · chain A against A4, TM-score 0.84
- 6LQU · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) · an experimental structure of the same protein · chain A against A4, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06679
- Elsewhere: UniProt Q06679 · AlphaFold DB Q06679
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