MolNFT v1 · #493007 · protein
AlphaFold monomer V2.0 prediction for U3 small nucleolar RNA- associated protein 25 (O74974)
O74974 · U3 small nucleolar RNA-associated protein 25: “AlphaFold monomer V2.0 prediction for U3 small nucleolar RNA- associated protein 25 (O74974)”. 11 pockets (best druggability 0.74). MolNFT v1 #493007 on GenesisL1: 3D structure…
- Accession
- O74974
- Type
- protein
- Length
- 652 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- U3 small nucleolar RNA-associated protein 25
- UniProt
- O74974
- Pockets
- 11 · best druggability 0.74
Structure
1 distinct chain · 49% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | U3 small nucleolar RNA-associated protein 25 | protein | 652 | 49% helix, 15% strand | O74974 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1046 | 0.74 | 0.77 | 89 | empty |
| 2 | 298 | 0.64 | 0.81 | 27 | empty |
| 3 | 433 | 0.62 | 0.77 | 59 | empty |
| 4 | 152 | 0.60 | 0.84 | 31 | empty |
| 5 | 101 | 0.51 | 0.82 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74974
- Elsewhere: UniProt O74974 · AlphaFold DB O74974
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