MolNFT v1 · #492563 · protein
AlphaFold monomer V2.0 prediction for urokinase-type plasminogen activator (Q5RF29)
Q5RF29: “AlphaFold monomer V2.0 prediction for urokinase-type plasminogen activator (Q5RF29)”. 5 pockets (best druggability 0.64). MolNFT v1 #492563 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5RF29
- Type
- protein
- Length
- 431 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- Urokinase-type plasminogen activator
- UniProt
- Q5RF29
- Pockets
- 5 · best druggability 0.64
Structure
1 distinct chain · 8% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Urokinase-type plasminogen activator | protein | 431 | 8% helix, 28% strand | Q5RF29 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 571 | 0.64 | 0.75 | 40 | empty |
| 2 | 332 | 0.58 | 0.77 | 31 | empty |
| 3 | 103 | 0.52 | 0.83 | 20 | empty |
| 4 | 116 | 0.39 | 0.75 | 21 | empty |
| 5 | 104 | 0.38 | 0.76 | 22 | empty |
Modifications
Observed in the structure: 12 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5RF29
- Elsewhere: UniProt Q5RF29 · AlphaFold DB Q5RF29
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