MolNFT v1 · #492562 · protein
AlphaFold monomer V2.0 prediction for urokinase-type plasminogen activator (P04185)
P04185: “AlphaFold monomer V2.0 prediction for urokinase-type plasminogen activator (P04185)”. 4 pockets (best druggability 0.64). MolNFT v1 #492562 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P04185
- Type
- protein
- Length
- 442 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- Urokinase-type plasminogen activator
- UniProt
- P04185
- Pockets
- 4 · best druggability 0.64
Structure
1 distinct chain · 7% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Urokinase-type plasminogen activator | protein | 442 | 7% helix, 29% strand | P04185 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 612 | 0.64 | 0.75 | 58 | empty |
| 2 | 83 | 0.55 | 0.86 | 19 | empty |
| 3 | 165 | 0.45 | 0.76 | 33 | empty |
| 4 | 179 | 0.45 | 0.74 | 24 | empty |
Modifications
Observed in the structure: 11 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04185
- Elsewhere: UniProt P04185 · AlphaFold DB P04185
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