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MolNFT v1 · #489822 · protein

AlphaFold monomer V2.0 prediction for DITRANS,POLYCIS-undecaprenyl- diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) (P60472)

P60472 · DITRANS,POLYCIS-undecaprenyl-diphosphate synthase…: “AlphaFold monomer V2.0 prediction for DITRANS,POLYCIS-undecaprenyl- diphosphate synthase…”. 3 pockets (best druggability 0.78). MolNFT v1 #489822 on GenesisL1: 3D structure…

Accession
P60472
Type
protein
Length
253 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x203931C4dCE9665F4d5cF5934d3Ae3C09C32cf88
Molecule
DITRANS,POLYCIS-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)
UniProt
P60472
Pockets
3 · best druggability 0.78

Structure

1 distinct chain · 44% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADITRANS,POLYCIS-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)protein25344% helix, 13% strandP60472

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14100.780.8750empty
2840.390.7822empty
3640.250.7214empty

Compared structures

  • 1X07 · Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg and IPP · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1X07 · Crystal structure of undecaprenyl pyrophosphate synthase in complex with mg and ipp · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1X06 · Crystal structure of undecaprenyl pyrophosphate synthase in complex with mg, ipp and fspp · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1X06 · Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg, IPP and Fspp · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1X08 · Crystal structure of D26A mutant upps in complex with mg, ipp and fspp · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1X08 · Crystal structure of D26A mutant UPPs in complex with Mg, IPP and FsPP · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1X09 · Crystal structure of the D26A mutant UPPs in complex with magnesium and isopentenyl… · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1X09 · Crystal structure of the D26A mutant upps in complex with magnesium and isopentenyl… · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 1V7U · Crystal structure of undecaprenyl pyrophosphate synthase with farnesyl pyrophosphate · an experimental structure of the same protein · chain A against A, TM-score 0.88
  • 1V7U · Crystal structure of Undecaprenyl Pyrophosphate Synthase with farnesyl pyrophosphate · an experimental structure of the same protein · chain A against A, TM-score 0.88
  • 1UEH · E. COLI undecaprenyl pyrophosphate synthase in complex with triton X- 100, magnesium and… · an experimental structure of the same protein · chain A against B, TM-score 0.84
  • 1UEH · E. coli undecaprenyl pyrophosphate synthase in complex with Triton X-100, magnesium and… · an experimental structure of the same protein · chain A against B, TM-score 0.84

Analyse

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