MolNFT v1 · #489106 · protein
AlphaFold monomer V2.0 prediction for urokinase plasminogen activator surface receptor (Q03405)
Q03405: “AlphaFold monomer V2.0 prediction for urokinase plasminogen activator surface receptor (Q03405)”. 3 pockets (best druggability 0.73). MolNFT v1 #489106 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q03405
- Type
- protein
- Length
- 335 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- Urokinase plasminogen activator surface receptor
- UniProt
- Q03405
- Pockets
- 3 · best druggability 0.73
Structure
1 distinct chain · 8% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Urokinase plasminogen activator surface receptor | protein | 335 | 8% helix, 40% strand | Q03405 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 685 | 0.73 | 0.79 | 58 | empty |
| 2 | 251 | 0.54 | 0.77 | 37 | empty |
| 3 | 94 | 0.41 | 0.78 | 18 | empty |
Modifications
Observed in the structure: 14 disulfide (disulfide).
Compared structures
- 3BT1 · Structure of urokinase receptor, urokinase and vitronectin complex · an experimental structure of the same protein · chain A against U, TM-score 0.79
- 3BT1 · Structure of urokinase receptor, urokinase and vitronectin complex · an experimental structure of the same protein · chain A against U, TM-score 0.79
- 4K24 · Structure of anti-upar Fab atn-658 in complex with upar · an experimental structure of the same protein · chain A against U, TM-score 0.78
- 4K24 · Structure of anti-uPAR Fab ATN-658 in complex with uPAR · an experimental structure of the same protein · chain A against U, TM-score 0.78
- 3U73 · Crystal structure of stabilized human upar mutant in complex with atf · an experimental structure of the same protein · chain A against U, TM-score 0.78
- 3U73 · Crystal structure of stabilized human uPAR mutant in complex with ATF · an experimental structure of the same protein · chain A against U, TM-score 0.78
- 4QTI · Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 · an experimental structure of the same protein · chain A against U, TM-score 0.76
- 4QTI · Crystal structure of human upar in complex with anti-upar Fab 8B12 · an experimental structure of the same protein · chain A against U, TM-score 0.76
- 2I9B · Crystal structure of atf-urokinase receptor complex · an experimental structure of the same protein · chain A against E, TM-score 0.76
- 2I9B · Crystal structure of ATF-urokinase receptor complex · an experimental structure of the same protein · chain A against E, TM-score 0.76
- 3BT2 · Structure of urokinase receptor, urokinase and vitronectin complex · an experimental structure of the same protein · chain A against U, TM-score 0.76
- 3BT2 · Structure of urokinase receptor, urokinase and vitronectin complex · an experimental structure of the same protein · chain A against U, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03405
- Elsewhere: UniProt Q03405 · AlphaFold DB Q03405
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.