GL1X · GenesisL1 explorer

MolNFT v1 · #487911 · protein

AlphaFold monomer V2.0 prediction for UTP--glucose-1-phosphate uridylyltransferase (Q16851)

Q16851: “AlphaFold monomer V2.0 prediction for UTP--glucose-1-phosphate uridylyltransferase (Q16851)”. 6 pockets (best druggability 0.73). MolNFT v1 #487911 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q16851
Type
protein
Length
508 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
Molecule
UTP--glucose-1-phosphate uridylyltransferase
UniProt
Q16851
Pockets
6 · best druggability 0.73

Structure

1 distinct chain · 37% helix, 27% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AUTP--glucose-1-phosphate uridylyltransferaseprotein50837% helix, 27% strandQ16851

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111170.730.7678empty
22510.650.8326empty
34770.620.7652empty
4680.390.7914empty
5550.370.8016empty

Compared structures

  • 4R7P · Human UDP-glucose pyrophosphorylase isoform 1 in complex with UDP-glucose · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 4R7P · Human udp-glucose pyrophosphorylase isoform 1 in complex with udp- glucose · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 3R2W · Crystal Structure of UDP-glucose Pyrophosphorylase of Homo Sapiens · an experimental structure of the same protein · chain A against D, TM-score 0.91
  • 3R2W · Crystal structure of udp-glucose pyrophosphorylase of homo sapiens · an experimental structure of the same protein · chain A against D, TM-score 0.91
  • 3R3I · Crystal Structure of C-terminal truncation of UDP-glucose Pyrophosphorylase of Homo… · an experimental structure of the same protein · chain A against B, TM-score 0.90
  • 3R3I · Crystal structure of C-terminal truncation of udp-glucose pyrophosphorylase of homo… · an experimental structure of the same protein · chain A against B, TM-score 0.90

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