MolNFT v1 · #487806 · protein
AlphaFold monomer V2.0 prediction for tyrosine-protein kinase receptor ufo (Q00993)
Q00993: “AlphaFold monomer V2.0 prediction for tyrosine-protein kinase receptor ufo (Q00993)”. 9 pockets (best druggability 0.70). MolNFT v1 #487806 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q00993
- Type
- protein
- Length
- 888 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xDd175FDc2561f3a80D6d56bCDE090F8cA47DD5f0
- Molecule
- Tyrosine-protein kinase receptor ufo
- UniProt
- Q00993
- Pockets
- 9 · best druggability 0.70
Structure
1 distinct chain · 18% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase receptor ufo | protein | 888 | 18% helix, 30% strand | Q00993 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 694 | 0.70 | 0.77 | 62 | empty |
| 2 | 381 | 0.58 | 0.76 | 40 | empty |
| 3 | 297 | 0.53 | 0.75 | 44 | empty |
| 4 | 103 | 0.42 | 0.77 | 15 | empty |
| 5 | 63 | 0.36 | 0.78 | 15 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00993
- Elsewhere: UniProt Q00993 · AlphaFold DB Q00993
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