MolNFT v1 · #486942 · protein

AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 11 (P51784)

P51784: “AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 11 (P51784)”. 13 pockets (best druggability 0.77). MolNFT v1 #486942 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P51784
Type: protein
Length: 963 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xDe2aE7Cc3d8e4f1cd20A4c886f7791E6261B7414
Molecule: Ubiquitin carboxyl-terminal hydrolase 11
UniProt: P51784
Pockets: 13 · best druggability 0.77

Structure

1 distinct chain · 24% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin carboxyl-terminal hydrolase 11	protein	963	24% helix, 25% strand	P51784

Pockets

13 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	785	0.77	0.81	78	empty
2	755	0.70	0.77	85	empty
3	58	0.70	0.97	20	empty
4	421	0.65	0.79	43	empty
5	157	0.58	0.82	27	empty

Compared structures

8OYP · Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate… · an experimental structure of the same protein · chain A against B, TM-score 0.39
4MEL · Crystal Structure of the human USP11 DUSP-UBL domains · an experimental structure of the same protein · chain A against A, TM-score 0.12
4MEL · Crystal structure of the human USP11 dusp-ubl domains · an experimental structure of the same protein · chain A against A, TM-score 0.12

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51784
Elsewhere: UniProt P51784 · AlphaFold DB P51784

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