MolNFT v1 · #484616 · protein

AlphaFold monomer V2.0 prediction for telomere zinc finger-associated protein (P10074)

P10074: “AlphaFold monomer V2.0 prediction for telomere zinc finger-associated protein (P10074)”. 3 pockets (best druggability 0.61). MolNFT v1 #484616 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P10074
Type: protein
Length: 688 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule: Telomere zinc finger-associated protein
UniProt: P10074
Pockets: 3 · best druggability 0.61

Structure

1 distinct chain · 30% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Telomere zinc finger-associated protein	protein	688	30% helix, 8% strand	P10074

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	340	0.61	0.78	34	empty
2	133	0.45	0.77	20	empty
3	66	0.34	0.76	14	empty

Compared structures

3B84 · Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3… · an experimental structure of the same protein · chain A against A, TM-score 0.13
3B84 · Crystal structure of the human btb domain of the krueppel related zinc finger protein 3… · an experimental structure of the same protein · chain A against A, TM-score 0.13
5YJ3 · Crystal structure of tzap and telomeric DNA complex · an experimental structure of the same protein · chain A against C, TM-score 0.06

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10074
Elsewhere: UniProt P10074 · AlphaFold DB P10074

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