MolNFT v1 · #484422 · protein
AlphaFold monomer V2.0 prediction for thymidylate synthase (Q8Z412)
Q8Z412: “AlphaFold monomer V2.0 prediction for thymidylate synthase (Q8Z412)”. 2 pockets (best druggability 0.75). MolNFT v1 #484422 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8Z412
- Type
- protein
- Length
- 264 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
- Molecule
- Thymidylate synthase
- UniProt
- Q8Z412
- Pockets
- 2 · best druggability 0.75
Structure
1 distinct chain · 34% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thymidylate synthase | protein | 264 | 34% helix, 26% strand | Q8Z412 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 485 | 0.75 | 0.83 | 45 | empty |
| 2 | 54 | 0.25 | 0.72 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8Z412
- Elsewhere: UniProt Q8Z412 · AlphaFold DB Q8Z412
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