MolNFT v1 · #484270 · protein
AlphaFold monomer V2.0 prediction for thymidylate synthase (Q9UWQ5)
Q9UWQ5: “AlphaFold monomer V2.0 prediction for thymidylate synthase (Q9UWQ5)”. 4 pockets (best druggability 0.74). MolNFT v1 #484270 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UWQ5
- Type
- protein
- Length
- 342 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x05CDDe9aA2Fa0C3667552a776E594bf1422198e0
- Molecule
- Thymidylate synthase
- UniProt
- Q9UWQ5
- Pockets
- 4 · best druggability 0.74
Structure
1 distinct chain · 35% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thymidylate synthase | protein | 342 | 35% helix, 23% strand | Q9UWQ5 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 455 | 0.74 | 0.84 | 40 | empty |
| 2 | 104 | 0.58 | 0.86 | 27 | empty |
| 3 | 82 | 0.37 | 0.76 | 14 | empty |
| 4 | 50 | 0.35 | 0.79 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UWQ5
- Elsewhere: UniProt Q9UWQ5 · AlphaFold DB Q9UWQ5
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