MolNFT v1 · #484215 · protein
AlphaFold monomer V2.0 prediction for thymidylate synthase (P0CS12)
P0CS12: “AlphaFold monomer V2.0 prediction for thymidylate synthase (P0CS12)”. 3 pockets (best druggability 0.73). MolNFT v1 #484215 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P0CS12
- Type
- protein
- Length
- 317 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF164267A353Fd1c28Ba0a1BF3b7A0eC5C501a949
- Molecule
- Thymidylate synthase
- UniProt
- P0CS12
- Pockets
- 3 · best druggability 0.73
Structure
1 distinct chain · 34% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thymidylate synthase | protein | 317 | 34% helix, 20% strand | P0CS12 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 460 | 0.73 | 0.83 | 40 | empty |
| 2 | 89 | 0.36 | 0.75 | 16 | empty |
| 3 | 54 | 0.28 | 0.75 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0CS12
- Elsewhere: UniProt P0CS12 · AlphaFold DB P0CS12
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