MolNFT v1 · #481143 · protein

AlphaFold monomer V2.0 prediction for thrombospondin-3 (P49746)

P49746: “AlphaFold monomer V2.0 prediction for thrombospondin-3 (P49746)”. 4 pockets (best druggability 0.74). MolNFT v1 #481143 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P49746
Type: protein
Length: 956 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
Molecule: Thrombospondin-3
UniProt: P49746
Pockets: 4 · best druggability 0.74

Structure

1 distinct chain · 13% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thrombospondin-3	protein	956	13% helix, 26% strand	P49746

Pockets

4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	957	0.74	0.78	100	empty
2	53	0.74	0.99	17	empty
3	425	0.58	0.75	37	empty
4	380	0.54	0.73	40	empty

Modifications

Observed in the structure: 22 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49746
Elsewhere: UniProt P49746 · AlphaFold DB P49746

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