MolNFT v1 · #481134 · protein
AlphaFold monomer V2.0 prediction for thrombospondin-1 (P35448)
P35448: “AlphaFold monomer V2.0 prediction for thrombospondin-1 (P35448)”. 6 pockets (best druggability 0.73). MolNFT v1 #481134 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P35448
- Type
- protein
- Length
- 1,173 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x64B78f4257919581cCE801d619C8253245b97Bc8
- Molecule
- Thrombospondin-1
- UniProt
- P35448
- Pockets
- 6 · best druggability 0.73
Structure
1 distinct chain · 10% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thrombospondin-1 | protein | 1173 | 10% helix, 27% strand | P35448 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 721 | 0.73 | 0.79 | 74 | empty |
| 2 | 306 | 0.62 | 0.79 | 41 | empty |
| 3 | 165 | 0.44 | 0.75 | 26 | empty |
| 4 | 69 | 0.32 | 0.75 | 16 | empty |
| 5 | 67 | 0.32 | 0.75 | 19 | empty |
Modifications
Observed in the structure: 33 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35448
- Elsewhere: UniProt P35448 · AlphaFold DB P35448
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