MolNFT v1 · #481117 · protein

AlphaFold monomer V2.0 prediction for 23S rRNA (ADENOSINE(1067)-2'-O)-methyltransferase (P18644)

P18644: “AlphaFold monomer V2.0 prediction for 23S rRNA (ADENOSINE(1067)-2'-O)-methyltransferase (P18644)”. 3 pockets (best druggability 0.54). MolNFT v1 #481117 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P18644
Type: protein
Length: 269 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x0CC4140Ba225D530b2DC080d22627144DEBB1186
Molecule: 23S rRNA (ADENOSINE(1067)-2'-O)-methyltransferase
UniProt: P18644
Pockets: 3 · best druggability 0.54

Structure

1 distinct chain · 37% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	23S rRNA (ADENOSINE(1067)-2'-O)-methyltransferase	protein	269	37% helix, 21% strand	P18644

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	127	0.54	0.82	22	empty
2	142	0.43	0.75	25	empty
3	55	0.31	0.77	15	empty

Compared structures

3GYQ · Structure of the Thiostrepton-Resistance Methyltransferase S-adenosyl-L-methionine Complex · an experimental structure of the same protein · chain A against A, TM-score 0.84
3GYQ · Structure of the thiostrepton-resistance methyltransferase S-adenosyl-L-methionine complex · an experimental structure of the same protein · chain A against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P18644
Elsewhere: UniProt P18644 · AlphaFold DB P18644

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