MolNFT v1 · #481060 · protein

AlphaFold monomer V2.0 prediction for tetraspanin-2 (O60636)

O60636: “AlphaFold monomer V2.0 prediction for tetraspanin-2 (O60636)”. 4 pockets (best druggability 0.59). MolNFT v1 #481060 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O60636
Type: protein
Length: 221 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
Molecule: Tetraspanin-2
UniProt: O60636
Pockets: 4 · best druggability 0.59

Structure

1 distinct chain · 81% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tetraspanin-2	protein	221	81% helix, 0% strand	O60636

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	138	0.59	0.83	20	empty
2	144	0.43	0.75	29	empty
3	71	0.32	0.74	11	empty
4	56	0.26	0.73	18	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60636
Elsewhere: UniProt O60636 · AlphaFold DB O60636

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