MolNFT v1 · #479730 · protein
AlphaFold monomer V2.0 prediction for thioredoxin reductase (P66011)
P66011: “AlphaFold monomer V2.0 prediction for thioredoxin reductase (P66011)”. 1 pocket (best druggability 0.78). MolNFT v1 #479730 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P66011
- Type
- protein
- Length
- 311 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
- Molecule
- Thioredoxin reductase
- UniProt
- P66011
- Pockets
- 1 · best druggability 0.78
Structure
1 distinct chain · 29% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thioredoxin reductase | protein | 311 | 29% helix, 31% strand | P66011 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 814 | 0.78 | 0.81 | 88 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4GCM · Crystal structure of a thioredoxine reductase (trxb) from staphylococcus aureus subsp.… · an experimental structure of the same protein · chain A against B, TM-score 0.77
- 4GCM · Crystal structure of a thioredoxine reductase (trxB) from Staphylococcus aureus subsp.… · an experimental structure of the same protein · chain A against B, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P66011
- Elsewhere: UniProt P66011 · AlphaFold DB P66011
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