MolNFT v1 · #479692 · protein
AlphaFold monomer V2.0 prediction for thioredoxin reductase (O84101)
O84101: “AlphaFold monomer V2.0 prediction for thioredoxin reductase (O84101)”. 4 pockets (best druggability 0.78). MolNFT v1 #479692 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O84101
- Type
- protein
- Length
- 312 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- Thioredoxin reductase
- UniProt
- O84101
- Pockets
- 4 · best druggability 0.78
Structure
1 distinct chain · 26% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thioredoxin reductase | protein | 312 | 26% helix, 29% strand | O84101 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 538 | 0.78 | 0.85 | 73 | empty |
| 2 | 95 | 0.39 | 0.76 | 17 | empty |
| 3 | 92 | 0.35 | 0.75 | 16 | empty |
| 4 | 60 | 0.28 | 0.74 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O84101
- Elsewhere: UniProt O84101 · AlphaFold DB O84101
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