MolNFT v1 · #479289 · protein
AlphaFold monomer V2.0 prediction for probable tRNA pseudouridine synthase B (Q7LWY0)
Q7LWY0: “AlphaFold monomer V2.0 prediction for probable tRNA pseudouridine synthase B (Q7LWY0)”. 3 pockets (best druggability 0.60). MolNFT v1 #479289 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q7LWY0
- Type
- protein
- Length
- 340 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- Probable tRNA pseudouridine synthase B
- UniProt
- Q7LWY0
- Pockets
- 3 · best druggability 0.60
Structure
1 distinct chain · 29% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable tRNA pseudouridine synthase B | protein | 340 | 29% helix, 31% strand | Q7LWY0 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 226 | 0.60 | 0.80 | 29 | empty |
| 2 | 104 | 0.37 | 0.74 | 13 | empty |
| 3 | 56 | 0.26 | 0.73 | 11 | empty |
Compared structures
- 3HAX · Crystal structure of a substrate-bound Gar1-minus H/ACA RNP from Pyrococcus furiosus · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 3HAX · Crystal structure of a substrate-bound GAR1-minus H/ACA rnp from pyrococcus furiosus · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 3HJW · Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 3HJW · Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 3HAY · Crystal structure of a substrate-bound full H/ACA RNP from Pyrococcus furiosus · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 3HAY · Crystal structure of a substrate-bound full H/ACA rnp from pyrococcus furiosus · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 2EY4 · Crystal Structure of a Cbf5-Nop10-Gar1 Complex · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2EY4 · Crystal structure of a CBF5-NOP10-GAR1 complex · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 3HJY · Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 3HJY · Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 3MQK · Cbf5-Nop10-Gar1 complex binding with 17mer RNA containing ACA trinucleotide · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 3MQK · CBF5-NOP10-GAR1 complex binding with 17MER RNA containing aca trinucleotide · an experimental structure of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7LWY0
- Elsewhere: UniProt Q7LWY0 · AlphaFold DB Q7LWY0
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