MolNFT v1 · #478168 · protein
AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily M member 6 (Q8CIR4)
Q8CIR4: “AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily M member 6…”. 20 pockets (best druggability 0.79). MolNFT v1 #478168 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8CIR4
- Type
- protein
- Length
- 2,028 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc5ddbFd578Ee8bf0Bb22bF47F38D91D88bE1AdDf
- Molecule
- Transient receptor potential cation channel subfamily M member 6
- UniProt
- Q8CIR4
- Pockets
- 20 · best druggability 0.79
Structure
1 distinct chain · 39% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transient receptor potential cation channel subfamily M member 6 | protein | 2028 | 39% helix, 8% strand | Q8CIR4 |
Pockets
20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 619 | 0.79 | 0.84 | 61 | empty |
| 2 | 449 | 0.71 | 0.82 | 37 | empty |
| 3 | 498 | 0.66 | 0.77 | 49 | empty |
| 4 | 156 | 0.60 | 0.83 | 24 | empty |
| 5 | 272 | 0.59 | 0.79 | 34 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8CIR4
- Elsewhere: UniProt Q8CIR4 · AlphaFold DB Q8CIR4
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